Lack of concordance between genetic diversity estimates at the molecular and quantitative-trait levels

Michael E. Pfrender, Ken Spitze, Justin Hicks, Kendall Morgan, Leigh Latta, Michael Lynch

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

In many applications of population genetics, particularly in the field of conservation biology, estimates of molecular diversity are used as surrogate indicators of less easily acquired measures of genetic variation for quantitative traits. The general validity of this approach to inferring levels of quantitative genetic variation within populations is called into question by the demonstration that estimates of molecular and quantitative-genetic variation are essentially uncorrelated in natural populations of Daphnia, one of the few organisms for which multiple estimates of both quantities are available. On the other hand, molecular measures of population subdivision seem to give conservatively low estimates of the degree of genetic subdivision at the level of quantitative traits. This suggests that although molecular markers provide little information on the level of genetic variation for quantitative traits within populations, they may be valid indicators of population subdivision for such characters.

Original languageEnglish (US)
Pages (from-to)263-269
Number of pages7
JournalConservation Genetics
Volume1
Issue number3
DOIs
StatePublished - Jan 1 2000
Externally publishedYes

Fingerprint

quantitative traits
genetic variation
quantitative genetics
founder effect
Population
Molecular Biology
Daphnia
molecular genetics
population genetics
Population Genetics
Biological Sciences
genetic markers
genetic diversity
organisms
indicator

Keywords

  • Genetic diversity
  • Heritability
  • Heterozygosity
  • Microsatellites

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics

Cite this

Lack of concordance between genetic diversity estimates at the molecular and quantitative-trait levels. / Pfrender, Michael E.; Spitze, Ken; Hicks, Justin; Morgan, Kendall; Latta, Leigh; Lynch, Michael.

In: Conservation Genetics, Vol. 1, No. 3, 01.01.2000, p. 263-269.

Research output: Contribution to journalArticle

Pfrender, Michael E. ; Spitze, Ken ; Hicks, Justin ; Morgan, Kendall ; Latta, Leigh ; Lynch, Michael. / Lack of concordance between genetic diversity estimates at the molecular and quantitative-trait levels. In: Conservation Genetics. 2000 ; Vol. 1, No. 3. pp. 263-269.
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