Label-free proteomic identification of endogenous, insulin-stimulated interaction partners of insulin receptor substrate-1

Medicine & Life Sciences

• Insulin Receptor Substrate Proteins 100%
• Proteomics 70%
• Insulin 52%
• Proteins 28%
• Immunoprecipitation 13%
• Protein Phosphatase 1 6%
• Protein Folding 5%
• Skeletal Muscle Fibers 5%
• Endoplasmic Reticulum Stress 5%
• Tandem Mass Spectrometry 4%
• Heat-Shock Proteins 4%
• Muscle Contraction 4%
• Actin Cytoskeleton 4%
• Epitopes 3%
• Insulin Resistance 3%
• Signal Transduction 3%
• Type 2 Diabetes Mellitus 3%

Chemical Compounds

• Insulin Derivative 78%
• Protein 31%
• Tandem Mass Spectrometry 17%
• Dephosphorylation 8%
• Protein Folding 7%
• Signal Transduction 7%
• Protein Synthesis 7%
• Reaction Stoichiometry 5%
• Resistance 4%
• Application 4%