Javaniside, a novel DNA cleavage agent from Alangium javanicum having an unusual oxindole skeleton

Ji Ma; Sidney M. Hecht

doi:10.1039/b402925a

Javaniside, a novel DNA cleavage agent from Alangium javanicum having an unusual oxindole skeleton

Ji Ma, Sidney M. Hecht

Research output: Contribution to journal › Article › peer-review

150 Scopus citations

Abstract

Bioassay-guided fractionation of an extract prepared from Alangium javanicum using an assay to monitor Cu²⁺-dependent DNA strand scission led to the isolation of javaniside, a new type of oxindole glycoside.

Original language	English (US)
Pages (from-to)	1190-1191
Number of pages	2
Journal	Chemical Communications
Volume	4
Issue number	10
DOIs	https://doi.org/10.1039/b402925a
State	Published - 2004
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b402925a

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title = "Javaniside, a novel DNA cleavage agent from Alangium javanicum having an unusual oxindole skeleton",

abstract = "Bioassay-guided fractionation of an extract prepared from Alangium javanicum using an assay to monitor Cu2+-dependent DNA strand scission led to the isolation of javaniside, a new type of oxindole glycoside.",

author = "Ji Ma and Hecht, {Sidney M.}",

year = "2004",

doi = "10.1039/b402925a",

language = "English (US)",

volume = "4",

pages = "1190--1191",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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T1 - Javaniside, a novel DNA cleavage agent from Alangium javanicum having an unusual oxindole skeleton

AU - Ma, Ji

AU - Hecht, Sidney M.

PY - 2004

Y1 - 2004

N2 - Bioassay-guided fractionation of an extract prepared from Alangium javanicum using an assay to monitor Cu2+-dependent DNA strand scission led to the isolation of javaniside, a new type of oxindole glycoside.

AB - Bioassay-guided fractionation of an extract prepared from Alangium javanicum using an assay to monitor Cu2+-dependent DNA strand scission led to the isolation of javaniside, a new type of oxindole glycoside.

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U2 - 10.1039/b402925a

DO - 10.1039/b402925a

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AN - SCOPUS:16644375516

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JO - Chemical Communications

JF - Chemical Communications

IS - 10

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Javaniside, a novel DNA cleavage agent from Alangium javanicum having an unusual oxindole skeleton

Abstract

ASJC Scopus subject areas

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