Isolation of geodiatoxins 2-4 from the marine sponge Geodia mesotriaena

George Pettit, John A. Rideout, Julia A. Hasler

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

1. In a previous study of the marine sponge Geodia mesotriaena von Lendenfeld for antineoplastic constituents, evidence was obtained for the presence of several toxins and geodiatoxin 1 was isolated. 2. Further separations guided by bioassay using CDF1 mice have led to the isolation of three additional chromoprotein toxins lethal at 8 mg/kg.

Original languageEnglish (US)
Pages (from-to)305-306
Number of pages2
JournalComparative Biochemistry and Physiology. Part C, Comparative
Volume96
Issue number2
DOIs
StatePublished - 1990

ASJC Scopus subject areas

  • Immunology
  • Pharmacology

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