Isolation of geodiatoxins 2-4 from the marine sponge Geodia mesotriaena

George Pettit, John A. Rideout, Julia A. Hasler

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

1. In a previous study of the marine sponge Geodia mesotriaena von Lendenfeld for antineoplastic constituents, evidence was obtained for the presence of several toxins and geodiatoxin 1 was isolated. 2. Further separations guided by bioassay using CDF1 mice have led to the isolation of three additional chromoprotein toxins lethal at 8 mg/kg.

Original languageEnglish (US)
Pages (from-to)305-306
Number of pages2
JournalComparative Biochemistry and Physiology. Part C, Comparative
Volume96
Issue number2
DOIs
StatePublished - 1990

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Geodia
Porifera
Biological Assay
Antineoplastic Agents

ASJC Scopus subject areas

  • Pharmacology
  • Immunology

Cite this

Isolation of geodiatoxins 2-4 from the marine sponge Geodia mesotriaena. / Pettit, George; Rideout, John A.; Hasler, Julia A.

In: Comparative Biochemistry and Physiology. Part C, Comparative, Vol. 96, No. 2, 1990, p. 305-306.

Research output: Contribution to journalArticle

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