Isolation and structure of spongilipid from the Republic of Singapore marine porifera Spongia cf. hispida

George Pettit; Timothy J. Bond; Delbert L. Herald; Martin Penny; Dennis L. Doubek; Michael D. Williams; Robin Pettit; John N A Hooper

doi:10.1139/v97-110

Isolation and structure of spongilipid from the Republic of Singapore marine porifera Spongia cf. hispida

George Pettit, Timothy J. Bond, Delbert L. Herald, Martin Penny, Dennis L. Doubek, Michael D. Williams, Robin Pettit, John N A Hooper

Research output: Contribution to journal › Article

7 Scopus citations

Abstract

Cell growth inhibitory (P388 lymphocytic leukemia) fractions from the purple marine sponge Spongia cf. hispida were employed to uncover a new biologically active monogalactosyl monoglyceride designated spongilipid (5a). The structure and absolute configuration of spongilipid was established by X-ray crystallography. Spongilipid specifically inhibited growth of the fecal opportunist Enterococcus faecalis.

Original language	English (US)
Pages (from-to)	920-925
Number of pages	6
Journal	Canadian Journal of Chemistry
Volume	75
Issue number	6
DOIs	https://doi.org/10.1139/v97-110
State	Published - Jan 1 1997

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Keywords

Marine sponge
Spongia hispida
Spongilipid

ASJC Scopus subject areas

Catalysis
Chemistry(all)
Organic Chemistry

Cite this

Pettit, G., Bond, T. J., Herald, D. L., Penny, M., Doubek, D. L., Williams, M. D., Pettit, R., & Hooper, J. N. A. (1997). Isolation and structure of spongilipid from the Republic of Singapore marine porifera Spongia cf. hispida. Canadian Journal of Chemistry, 75(6), 920-925. https://doi.org/10.1139/v97-110

Isolation and structure of spongilipid from the Republic of Singapore marine porifera Spongia cf. hispida. / Pettit, George; Bond, Timothy J.; Herald, Delbert L.; Penny, Martin; Doubek, Dennis L.; Williams, Michael D.; Pettit, Robin; Hooper, John N A.

In: Canadian Journal of Chemistry, Vol. 75, No. 6, 01.01.1997, p. 920-925.

Research output: Contribution to journal › Article

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10.1139/v97-110