Isolation and structure of spongilipid from the Republic of Singapore marine porifera Spongia cf. hispida

George Pettit; Timothy J. Bond; Delbert L. Herald; Martin Penny; Dennis L. Doubek; Michael D. Williams; Robin Pettit; John N A Hooper

doi:10.1139/v97-110

Isolation and structure of spongilipid from the Republic of Singapore marine porifera Spongia cf. hispida

George Pettit, Timothy J. Bond, Delbert L. Herald, Martin Penny, Dennis L. Doubek, Michael D. Williams, Robin Pettit, John N A Hooper

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Cell growth inhibitory (P388 lymphocytic leukemia) fractions from the purple marine sponge Spongia cf. hispida were employed to uncover a new biologically active monogalactosyl monoglyceride designated spongilipid (5a). The structure and absolute configuration of spongilipid was established by X-ray crystallography. Spongilipid specifically inhibited growth of the fecal opportunist Enterococcus faecalis.

Original language	English (US)
Pages (from-to)	920-925
Number of pages	6
Journal	Canadian Journal of Chemistry
Volume	75
Issue number	6
DOIs	https://doi.org/10.1139/v97-110
State	Published - Jan 1 1997

Keywords

Marine sponge
Spongia hispida
Spongilipid

ASJC Scopus subject areas

Catalysis
Chemistry(all)
Organic Chemistry

Access to Document

10.1139/v97-110

Cite this

Isolation and structure of spongilipid from the Republic of Singapore marine porifera Spongia cf. hispida. / Pettit, George; Bond, Timothy J.; Herald, Delbert L.; Penny, Martin; Doubek, Dennis L.; Williams, Michael D.; Pettit, Robin; Hooper, John N A.

In: Canadian Journal of Chemistry, Vol. 75, No. 6, 01.01.1997, p. 920-925.

Research output: Contribution to journal › Article › peer-review

@article{79605037f61d4ca4b2ceeb60f6d49b7f,

title = "Isolation and structure of spongilipid from the Republic of Singapore marine porifera Spongia cf. hispida",

abstract = "Cell growth inhibitory (P388 lymphocytic leukemia) fractions from the purple marine sponge Spongia cf. hispida were employed to uncover a new biologically active monogalactosyl monoglyceride designated spongilipid (5a). The structure and absolute configuration of spongilipid was established by X-ray crystallography. Spongilipid specifically inhibited growth of the fecal opportunist Enterococcus faecalis.",

keywords = "Marine sponge, Spongia hispida, Spongilipid",

author = "George Pettit and Bond, {Timothy J.} and Herald, {Delbert L.} and Martin Penny and Doubek, {Dennis L.} and Williams, {Michael D.} and Robin Pettit and Hooper, {John N A}",

year = "1997",

month = jan,

day = "1",

doi = "10.1139/v97-110",

language = "English (US)",

volume = "75",

pages = "920--925",

journal = "Canadian Journal of Chemistry",

issn = "0008-4042",

publisher = "National Research Council of Canada",

number = "6",

}

TY - JOUR

T1 - Isolation and structure of spongilipid from the Republic of Singapore marine porifera Spongia cf. hispida

AU - Pettit, George

AU - Bond, Timothy J.

AU - Herald, Delbert L.

AU - Penny, Martin

AU - Doubek, Dennis L.

AU - Williams, Michael D.

AU - Pettit, Robin

AU - Hooper, John N A

PY - 1997/1/1

Y1 - 1997/1/1

N2 - Cell growth inhibitory (P388 lymphocytic leukemia) fractions from the purple marine sponge Spongia cf. hispida were employed to uncover a new biologically active monogalactosyl monoglyceride designated spongilipid (5a). The structure and absolute configuration of spongilipid was established by X-ray crystallography. Spongilipid specifically inhibited growth of the fecal opportunist Enterococcus faecalis.

AB - Cell growth inhibitory (P388 lymphocytic leukemia) fractions from the purple marine sponge Spongia cf. hispida were employed to uncover a new biologically active monogalactosyl monoglyceride designated spongilipid (5a). The structure and absolute configuration of spongilipid was established by X-ray crystallography. Spongilipid specifically inhibited growth of the fecal opportunist Enterococcus faecalis.

KW - Marine sponge

KW - Spongia hispida

KW - Spongilipid

UR - http://www.scopus.com/inward/record.url?scp=0031163784&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031163784&partnerID=8YFLogxK

U2 - 10.1139/v97-110

DO - 10.1139/v97-110

M3 - Article

AN - SCOPUS:0031163784

VL - 75

SP - 920

EP - 925

JO - Canadian Journal of Chemistry

JF - Canadian Journal of Chemistry

SN - 0008-4042

IS - 6

ER -

Isolation and structure of spongilipid from the Republic of Singapore marine porifera Spongia cf. hispida

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this