Isolation and structure of phakellistatin 2 from the eastern indian ocean marine sponge phakellia carteri

George Pettit, Rui Tan, Michael D. Williams, Larry Tackett, Jean M. Schmidt, Ronald L. Cerny, John N A Hooper

Research output: Contribution to journalArticle

45 Scopus citations

Abstract

The marine sponge Phakellia carteri indigenous to the Republic of the Comoros was found to contain a new cell growth inhibitory (P388 cell line ED50 0.34 μg/ml) cyclo-heptapeptide named phakellistatin 2.

Original languageEnglish (US)
Pages (from-to)2869-2874
Number of pages6
JournalBioorganic and Medicinal Chemistry Letters
Volume3
Issue number12
DOIs
StatePublished - Dec 1993

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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    Pettit, G., Tan, R., Williams, M. D., Tackett, L., Schmidt, J. M., Cerny, R. L., & Hooper, J. N. A. (1993). Isolation and structure of phakellistatin 2 from the eastern indian ocean marine sponge phakellia carteri. Bioorganic and Medicinal Chemistry Letters, 3(12), 2869-2874. https://doi.org/10.1016/S0960-894X(01)80781-2