The unusual cyclodepsipeptide dolastatin 17 (1) was isolated from the Papua New Guinea sea hare Dolabella auricularia and found to contain a new acetylenic β-amino acid designated dolayne (Doy). Dolastatin 17 exhibited significant human cancer cell growth inhibitory activity (GI50 0.45-0.74 μg/mL range).
|Original language||English (US)|
|Number of pages||6|
|State||Published - Dec 1 1998|
ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry