@article{c88d7862d2d84a77b451c941c1406999,
title = "Isolation and structure of bryostatins 14 and 15",
abstract = "Further investigation of constituents from the marine bryozoan Bugula neritina employing new 1,000 kg recollections from the Gulf of Mexico and Eastern Pacific Ocean (California) has led to isolation and structural determination of two previously undetected members of the bryostatin (1-13) series, bryostatins 14 (14) and 15 (15). Structural analyses were conducted primarily with high field (400 MHz) NMR and high resolution mass spectral techniques. Both new bryostatins significantly inhibited growth of the P388 lymphocytic leukemia.",
author = "George Pettit and F. Gao and D. Sengupta and Coll., {J. C.} and Herald, {C. L.} and Doubek, {D. L.} and Schmidt, {J. M.} and {van Camp}, {J. R.} and Rudloe, {J. J.} and Nieman, {R. A.}",
note = "Funding Information: ACKNOWLEDGMENT For indispensable financial support we thank: the U. S. National Cancer Institute, DHHS, Outstanding Investigator Grant CA-44344-OlAl and Grants CA-16049-05-12; National Cooperative Drug Discovery Group Grant AI 25696-02-03; the Fannie E. Rippel Foundation; the Robert B. Dalton Endowment,E leanor W. Libby and the Waddell Foundation (Donald Ware); the Arizona Disease Control Research Commission; U. S. Army Medical Research and Medical Command Grant No. DAMD17-89-z-9021; the Ladies Auxiliary, V.F.W., Dept. of Arizona; and the Eagles Art EhrmannC ancer Fund. Other assistance was provided by Dr. F. M. Hogan and Mr. W. Schulz, the NSF Regional Instrumentation Facility in Nebraska (Grant No. CHE-8620177) and National Science Foundation Grant No. CHE-8409644. REFERENCES number 225. For part 224 refer to Pettit, G. R.; Gao, F.",
year = "1991",
doi = "10.1016/S0040-4020(01)80873-5",
language = "English (US)",
volume = "47",
pages = "3601--3610",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier Limited",
number = "22",
}