Isolation and Characterization of Strongylostatin 1

George Pettit, C. L. Herald, L. D. Vanell

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

The well-known green sea urchin Strongylocentrotus drobachiensis (Müller) has been found to contain a new glycoprotein antineoplastic agent. The glycoprotein was found to produce 35-53(7 life extension in the P388 murine lymphocytic leukemia system and has been designated strongylostatin 1. Because of the toxicity of strongylostatin 1 it may also be a constituent of Strongylocentrotus drobachiensis venom.

Original languageEnglish (US)
Pages (from-to)407-409
Number of pages3
JournalJournal of Natural Products
Volume42
Issue number4
DOIs
StatePublished - Jan 1 1979

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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