Isolation and characterization of lytechinastatin

George Pettit, John A. Rideout, Julia A. Hasler, Dennis L. Doubek, Peter R. Reucroft

Research output: Contribution to journalArticle

5 Scopus citations


The venomous marine animal Lytechinus variegatus (Lamarck) has been found to contain an antineoplastic glycoprotein. Separation of an aqueous extract of this Western Atlantic sea urchin by a series of macro reticular resin (or centrifugation) and gel permeation chromatographic sequences led to the new glycoprotein designated lytechinastatin.

Original languageEnglish (US)
Pages (from-to)713-716
Number of pages4
JournalJournal of Natural Products
Issue number6
StatePublished - Nov 1981

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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    Pettit, G., Rideout, J. A., Hasler, J. A., Doubek, D. L., & Reucroft, P. R. (1981). Isolation and characterization of lytechinastatin. Journal of Natural Products, 44(6), 713-716.