Inversion of Many-Beam Bragg Intensities for Phasing by Iterated Projections: Removal of Multiple Scattering Artifacts from Diffraction Data

Jeffrey J. Donatelli, John C.H. Spence

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

An iterated projection algorithm (N-Phaser) is developed that reconstructs a scattering potential from N-beam multiple Bragg scattered intensities. The method may be used to eliminate multiple scattering artifacts from electron diffraction data, solving the phase problem and increasing the thicknesses of samples used in materials science, solid-state chemistry, and small molecule crystallography. For high-energy transmission electron diffraction, we show that the algorithm recovers accurate complex structure factors from a wide range of thicknesses, orientations, and relativistic beam energies, and does not require known thickness or atomic-resolution data if sufficient multiple scattering occurs. Extensions to Cryo-electron microscopy and Micro-electron diffraction are suggested.

Original languageEnglish (US)
Article number065502
JournalPhysical Review Letters
Volume125
Issue number6
DOIs
StatePublished - Aug 7 2020

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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