Abstract
Intrauterine photoacoustic and ultrasound imaging are probe-based imaging modalities with translational potential for use in detecting endometrial diseases. This deep-tissue imaging probe design allows for the retrofitting of commercially available endometrial sampling curettes. The imaging probe presented here has a 2.92-mm diameter and approximate length of 26 cm, which allows for entry into the human endometrial cavity, making it possible to use photoacoustic imaging and high-resolution ultrasound to characterize the uterus. We demonstrate the imaging probes' ability to provide structural information of an excised pig uterus using ultrasound imaging and detect photoacoustic signals at a radial depth of 1 cm.
Original language | English (US) |
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Article number | 046008 |
Journal | Journal of biomedical optics |
Volume | 23 |
Issue number | 4 |
DOIs | |
State | Published - Apr 1 2018 |
Keywords
- deep-tissue imaging
- endometrial cancer
- photoacoustic endoscopy
- probe
- ultrasound imaging
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Atomic and Molecular Physics, and Optics
- Biomedical Engineering