Intracerebroventricular injection of ostrich β-endorphin to satiated pigeons induces hyperphagia but not hyperdipsia

Pierre Deviche, Günter Schepers

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Satiated pigeons received intracerebroventricular injections of either ostrich (0.06, 0.3 and 1.5 nmoles) or human (0.06 and 1.5 nmoles) β-endorphin, or a control solution, and their consumption of food and water was monitored during the half hour after these treatments. At each administered dose, ostrich β-endorphin enhanced food without altering water intake. By contrast, human β-endorphin did not induce any reliable alteration either of feeding or drinking. Together with previous studies performed in pigeons with opiate antagonists, these results suggest that the feeding system of pigeons is modulated by an endorphinergic mechanism. By contrast, no evidence exists so far that such a mechanism operates for controlling drinking, as appears to be the case in mammals.

Original languageEnglish (US)
Pages (from-to)691-694
Number of pages4
JournalPeptides
Volume5
Issue number4
DOIs
StatePublished - 1984
Externally publishedYes

Keywords

  • Beta-endorphin
  • Drinking
  • Endorphins
  • Feeding
  • Opiates
  • Opioid peptides
  • Pigeon

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Endocrinology
  • Cellular and Molecular Neuroscience

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