Integrated microsystem for classification, sorting, and storage of cellular nuclei based on DNA content from a tissue biopsy

Mark Holl, Thomas Paulson, Brian Rabkin, Erin Gibbons, Turgut Kosar, Deirdre Meldrum

Research output: Contribution to journalConference article

Abstract

The problem of preparing clean DNA derived from clinical samples remains one of the most difficult challenges to reducing laboratory scale distributed processesing systems into integrated micro total analysis systems. This study provides a solid analysis and set of design alternatives to achieve this significant goal. The microsystem design is intended to replace labor intensive procedures requiring highly trained and skilled laboratory personnel. An exploratory design is presented for an integrated, automated microsystem.

Original languageEnglish (US)
Pages (from-to)S-100
JournalAnnals of Biomedical Engineering
Volume28
Issue numberSUPPL. 1
StatePublished - Dec 1 2000
Externally publishedYes
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: Oct 12 2000Oct 14 2000

ASJC Scopus subject areas

  • Biomedical Engineering

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