Inorganic Nanomaterials for Soft Tissue Repair and Regeneration

Russell Urie, Deepanjan Ghosh, Inam Ridha, Kaushal Rege

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

Inorganic nanomaterials have witnessed significant advances in areas of medicine including cancer therapy, imaging, and drug delivery, but their use in soft tissue repair and regeneration is in its infancy. Metallic, ceramic, and carbon allotrope nanoparticles have shown promise in facilitating tissue repair and regeneration. Inorganic nanomaterials have been employed to improve stem cell engraftment in cellular therapy, material mechanical stability in tissue repair, electrical conductivity in nerve and cardiac regeneration, adhesion strength in tissue approximation, and antibacterial capacity in wound dressings. These nanomaterials have also been used to improve or replace common surgical materials and restore functionality to damaged tissue. We provide a comprehensive overview of inorganic nanomaterials in tissue repair and regeneration, and discuss their promise and limitations for eventual translation to the clinic.

Original languageEnglish (US)
Pages (from-to)353-374
Number of pages22
JournalAnnual Review of Biomedical Engineering
Volume20
DOIs
StatePublished - Jun 4 2018

Fingerprint

Nanostructures
Nanostructured materials
Regeneration
Repair
Tissue
Electric Conductivity
Nerve Regeneration
Mechanical stability
Bond strength (materials)
Ceramics
Bandages
Stem cells
Drug delivery
Nanoparticles
Medicine
Stem Cells
Carbon
Imaging techniques
Drug Therapy
Wounds and Injuries

Keywords

  • antibacterial
  • carbon nanomaterials
  • cardiac repair
  • gold nanoparticles
  • inflammation
  • laser sealing
  • neural repair
  • tissue adhesives
  • wound healing

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biomedical Engineering

Cite this

Inorganic Nanomaterials for Soft Tissue Repair and Regeneration. / Urie, Russell; Ghosh, Deepanjan; Ridha, Inam; Rege, Kaushal.

In: Annual Review of Biomedical Engineering, Vol. 20, 04.06.2018, p. 353-374.

Research output: Contribution to journalReview article

Urie, Russell ; Ghosh, Deepanjan ; Ridha, Inam ; Rege, Kaushal. / Inorganic Nanomaterials for Soft Tissue Repair and Regeneration. In: Annual Review of Biomedical Engineering. 2018 ; Vol. 20. pp. 353-374.
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