Inhibitors of DNA polymerase β from Schoepfia californica

Jie Chen, Yu Huan Zhang, Li Kai Wang, Steven J. Sucheck, Angela M. Snow, Sidney Hecht

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Abstract

Fractionation of a hexane extract prepared from the plant Schoepfia californica was carried out by bioassay guided fractionation, affording five inhibitors of DNA polymerase β; four of these were shown to be anacardic acid and structurally related derivatives, while the fifth was oleic acid.

Original languageEnglish (US)
Pages (from-to)2769-2770
Number of pages2
JournalChemical Communications
Issue number24
StatePublished - Dec 21 1998
Externally publishedYes

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Nucleic Acid Synthesis Inhibitors
Fractionation
Bioassay
Plant Extracts
Hexanes
Oleic Acid
Derivatives
anacardic acid

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Chen, J., Zhang, Y. H., Wang, L. K., Sucheck, S. J., Snow, A. M., & Hecht, S. (1998). Inhibitors of DNA polymerase β from Schoepfia californica. Chemical Communications, (24), 2769-2770.

Inhibitors of DNA polymerase β from Schoepfia californica. / Chen, Jie; Zhang, Yu Huan; Wang, Li Kai; Sucheck, Steven J.; Snow, Angela M.; Hecht, Sidney.

In: Chemical Communications, No. 24, 21.12.1998, p. 2769-2770.

Research output: Contribution to journalArticle

Chen, J, Zhang, YH, Wang, LK, Sucheck, SJ, Snow, AM & Hecht, S 1998, 'Inhibitors of DNA polymerase β from Schoepfia californica', Chemical Communications, no. 24, pp. 2769-2770.
Chen J, Zhang YH, Wang LK, Sucheck SJ, Snow AM, Hecht S. Inhibitors of DNA polymerase β from Schoepfia californica. Chemical Communications. 1998 Dec 21;(24):2769-2770.
Chen, Jie ; Zhang, Yu Huan ; Wang, Li Kai ; Sucheck, Steven J. ; Snow, Angela M. ; Hecht, Sidney. / Inhibitors of DNA polymerase β from Schoepfia californica. In: Chemical Communications. 1998 ; No. 24. pp. 2769-2770.
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