TY - GEN
T1 - Influence of Transcranial Electrical Stimulation (TES) waveforms on neural excitability of a realistic axon
T2 - 43rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2021
AU - Sahu, Sulagna
AU - Chauhan, Munish
AU - Sajib, Saurav Z.K.
AU - Sadleir, Rosalind J.
N1 - Publisher Copyright:
© 2021 IEEE.
PY - 2021
Y1 - 2021
N2 - Neuromodulation caused by transcranial electrical stimulation (TES) has been used successfully to treat various neuro-degenerative diseases. Simulation models provide an essential tool to study brain and nerve stimulation. Simulation models of TES provide an opportunity to research personalization of therapy without extensive animal and human testing. A computer model of a realistic sensory axon was built by finding actual geometry of the trigeminal nerve through tractography. A finite element model of the head was solved to obtain electric potential distribution caused by TES. Different waveforms were defined to test transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) with varying amplitude and frequency. Neural activity patterns were observed. The strength-duration curve was plotted to verify the model.
AB - Neuromodulation caused by transcranial electrical stimulation (TES) has been used successfully to treat various neuro-degenerative diseases. Simulation models provide an essential tool to study brain and nerve stimulation. Simulation models of TES provide an opportunity to research personalization of therapy without extensive animal and human testing. A computer model of a realistic sensory axon was built by finding actual geometry of the trigeminal nerve through tractography. A finite element model of the head was solved to obtain electric potential distribution caused by TES. Different waveforms were defined to test transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) with varying amplitude and frequency. Neural activity patterns were observed. The strength-duration curve was plotted to verify the model.
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U2 - 10.1109/EMBC46164.2021.9629948
DO - 10.1109/EMBC46164.2021.9629948
M3 - Conference contribution
C2 - 34892651
AN - SCOPUS:85122540887
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 6725
EP - 6727
BT - 43rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2021
PB - Institute of Electrical and Electronics Engineers Inc.
Y2 - 1 November 2021 through 5 November 2021
ER -