Influence of caffeine on blood lactate response during incremental exercise

Glenn Gaesser, R. G. Rich

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

To test the hypothesis that caffeine ingestion prior to exercise would delay the onset of blood lactate accumulation, eight male subjects were studied during incremental exercise to maximal work rates on a cycle ergometer under two conditions: 1 h after ingestion of 200 ml of either decaffeinated, calorie-free cola (control trial) or the same cola drink with 5 mg caffeine/kg body weight added (caffeine trial). Maximal exercise values for oxygen consumption (V̇O2max), ventilation, heart rate, respiratory exchange ratio (R), work rate, and blood lactate were not affected by caffeine. Submaximal exercise V̇O2, ventilation, and R also were unaffected by caffeine. During the caffeine trial, submaximal exercise blood lactate was significantly higher and heart rate significantly lower than during the control trial (P < 0.05). The lower exercise heart rate at the same V̇O2 resulted in a significantly greater O2 pulse during all submaximal exercise intensities for the caffeine trial (P < 0.05). Data on R indicated that caffeine had no effect on substrate utilization during exercise. Data on exercise blood lactate response suggested that caffeine does not delay and may accelerate the onset of blood lactate accumulation during incremental exercise. When defined as either a 'breakpoint', Δl mM (above resting lactate), or fixed level of 4 mM, the lactate threshold (LT) did not differ between caffeine and control trials. However, in using a 2 mM lactate level as a criterion, the LT during the caffeine trial (2.13 ± 0.22 l · min-1) was significantly (P < 0.05) lower than during the control trial (2.71 ± 0.17 l·min-1). Therefore, rejection of our hypothesis was independent of the definition of the LT. However, conclusions regarding the opposite hypothesis (i.e., that caffeine would lower the LT) were dependent upon the definition of the LT.

Original languageEnglish (US)
Pages (from-to)207-211
Number of pages5
JournalInternational Journal of Sports Medicine
Volume6
Issue number4
StatePublished - 1985
Externally publishedYes

Fingerprint

Caffeine
Lactic Acid
Heart Rate
Ventilation
Eating
Oxygen Consumption
Body Weight

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Public Health, Environmental and Occupational Health
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Influence of caffeine on blood lactate response during incremental exercise. / Gaesser, Glenn; Rich, R. G.

In: International Journal of Sports Medicine, Vol. 6, No. 4, 1985, p. 207-211.

Research output: Contribution to journalArticle

@article{2bec98948aeb44d3aa6428815f4c99b0,
title = "Influence of caffeine on blood lactate response during incremental exercise",
abstract = "To test the hypothesis that caffeine ingestion prior to exercise would delay the onset of blood lactate accumulation, eight male subjects were studied during incremental exercise to maximal work rates on a cycle ergometer under two conditions: 1 h after ingestion of 200 ml of either decaffeinated, calorie-free cola (control trial) or the same cola drink with 5 mg caffeine/kg body weight added (caffeine trial). Maximal exercise values for oxygen consumption (V̇O2max), ventilation, heart rate, respiratory exchange ratio (R), work rate, and blood lactate were not affected by caffeine. Submaximal exercise V̇O2, ventilation, and R also were unaffected by caffeine. During the caffeine trial, submaximal exercise blood lactate was significantly higher and heart rate significantly lower than during the control trial (P < 0.05). The lower exercise heart rate at the same V̇O2 resulted in a significantly greater O2 pulse during all submaximal exercise intensities for the caffeine trial (P < 0.05). Data on R indicated that caffeine had no effect on substrate utilization during exercise. Data on exercise blood lactate response suggested that caffeine does not delay and may accelerate the onset of blood lactate accumulation during incremental exercise. When defined as either a 'breakpoint', Δl mM (above resting lactate), or fixed level of 4 mM, the lactate threshold (LT) did not differ between caffeine and control trials. However, in using a 2 mM lactate level as a criterion, the LT during the caffeine trial (2.13 ± 0.22 l · min-1) was significantly (P < 0.05) lower than during the control trial (2.71 ± 0.17 l·min-1). Therefore, rejection of our hypothesis was independent of the definition of the LT. However, conclusions regarding the opposite hypothesis (i.e., that caffeine would lower the LT) were dependent upon the definition of the LT.",
author = "Glenn Gaesser and Rich, {R. G.}",
year = "1985",
language = "English (US)",
volume = "6",
pages = "207--211",
journal = "International Journal of Sports Medicine",
issn = "0172-4622",
publisher = "Georg Thieme Verlag",
number = "4",

}

TY - JOUR

T1 - Influence of caffeine on blood lactate response during incremental exercise

AU - Gaesser, Glenn

AU - Rich, R. G.

PY - 1985

Y1 - 1985

N2 - To test the hypothesis that caffeine ingestion prior to exercise would delay the onset of blood lactate accumulation, eight male subjects were studied during incremental exercise to maximal work rates on a cycle ergometer under two conditions: 1 h after ingestion of 200 ml of either decaffeinated, calorie-free cola (control trial) or the same cola drink with 5 mg caffeine/kg body weight added (caffeine trial). Maximal exercise values for oxygen consumption (V̇O2max), ventilation, heart rate, respiratory exchange ratio (R), work rate, and blood lactate were not affected by caffeine. Submaximal exercise V̇O2, ventilation, and R also were unaffected by caffeine. During the caffeine trial, submaximal exercise blood lactate was significantly higher and heart rate significantly lower than during the control trial (P < 0.05). The lower exercise heart rate at the same V̇O2 resulted in a significantly greater O2 pulse during all submaximal exercise intensities for the caffeine trial (P < 0.05). Data on R indicated that caffeine had no effect on substrate utilization during exercise. Data on exercise blood lactate response suggested that caffeine does not delay and may accelerate the onset of blood lactate accumulation during incremental exercise. When defined as either a 'breakpoint', Δl mM (above resting lactate), or fixed level of 4 mM, the lactate threshold (LT) did not differ between caffeine and control trials. However, in using a 2 mM lactate level as a criterion, the LT during the caffeine trial (2.13 ± 0.22 l · min-1) was significantly (P < 0.05) lower than during the control trial (2.71 ± 0.17 l·min-1). Therefore, rejection of our hypothesis was independent of the definition of the LT. However, conclusions regarding the opposite hypothesis (i.e., that caffeine would lower the LT) were dependent upon the definition of the LT.

AB - To test the hypothesis that caffeine ingestion prior to exercise would delay the onset of blood lactate accumulation, eight male subjects were studied during incremental exercise to maximal work rates on a cycle ergometer under two conditions: 1 h after ingestion of 200 ml of either decaffeinated, calorie-free cola (control trial) or the same cola drink with 5 mg caffeine/kg body weight added (caffeine trial). Maximal exercise values for oxygen consumption (V̇O2max), ventilation, heart rate, respiratory exchange ratio (R), work rate, and blood lactate were not affected by caffeine. Submaximal exercise V̇O2, ventilation, and R also were unaffected by caffeine. During the caffeine trial, submaximal exercise blood lactate was significantly higher and heart rate significantly lower than during the control trial (P < 0.05). The lower exercise heart rate at the same V̇O2 resulted in a significantly greater O2 pulse during all submaximal exercise intensities for the caffeine trial (P < 0.05). Data on R indicated that caffeine had no effect on substrate utilization during exercise. Data on exercise blood lactate response suggested that caffeine does not delay and may accelerate the onset of blood lactate accumulation during incremental exercise. When defined as either a 'breakpoint', Δl mM (above resting lactate), or fixed level of 4 mM, the lactate threshold (LT) did not differ between caffeine and control trials. However, in using a 2 mM lactate level as a criterion, the LT during the caffeine trial (2.13 ± 0.22 l · min-1) was significantly (P < 0.05) lower than during the control trial (2.71 ± 0.17 l·min-1). Therefore, rejection of our hypothesis was independent of the definition of the LT. However, conclusions regarding the opposite hypothesis (i.e., that caffeine would lower the LT) were dependent upon the definition of the LT.

UR - http://www.scopus.com/inward/record.url?scp=0022255091&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022255091&partnerID=8YFLogxK

M3 - Article

C2 - 4044104

AN - SCOPUS:0022255091

VL - 6

SP - 207

EP - 211

JO - International Journal of Sports Medicine

JF - International Journal of Sports Medicine

SN - 0172-4622

IS - 4

ER -