Influence of aging on the in vivo properties of human patellar tendon

C. C. Carroll, Jared Dickinson, J. M. Haus, G. A. Lee, C. J. Hollon, P. Aagaard, S. P. Magnusson, T. A. Trappe

Research output: Contribution to journalArticle

94 Citations (Scopus)

Abstract

Tendons are important for optimal muscle force transfer to bone and play a key role in functional ability. Changes in tendon properties with aging could contribute to declines in physical function commonly associated with aging. We investigated the in vivo mechanical properties of the patellar tendon in 37 men and women [11 young (27 ± 1 yr) and 26 old (65 ± 1 yr)] using ultrasonography and magnetic resonance imaging (MRI). Patella displacement relative to the tibia was monitored with ultrasonography during ramped isometric contractions of the knee extensors, and MRI was used to determine tendon cross-sectional area (CSA) and signal intensity. At peak force, patellar tendon deformation, stress, and strain were 13 (P = 0.05), 19, and 12% less in old compared with young (P < 0.05). Additionally, deformation, stiffness, stress, CSA, and length were 18, 35, 41, 28, and 11% greater (P < 0.05), respectively, in men compared with women. After normalization of mechanical properties to a common force, no age differences were apparent; however, stress and strain were 26 and 22% higher, respectively, in women compared with men (P < 0.05). CSA and signal intensity decreased 12 and 24%, respectively, with aging (P < 0.05) in the midregion of the tendon. These data suggest that differences in patellar tendon in vivo mechanical properties with aging are more related to force output rather than an age effect. In contrast, the decrease in signal intensity indirectly suggests that the internal milieu of the tendon is altered with aging; however, the physiological and functional consequence of this finding requires further study.

Original languageEnglish (US)
Pages (from-to)1907-1915
Number of pages9
JournalJournal of Applied Physiology
Volume105
Issue number6
DOIs
StatePublished - Dec 2008
Externally publishedYes

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Patellar Ligament
Tendons
Ultrasonography
Magnetic Resonance Imaging
Isometric Contraction
Patella
Tibia
Knee
Bone and Bones
Muscles

Keywords

  • Stress-strain relationship
  • Tendon injury
  • Ultrasonography

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

Cite this

Carroll, C. C., Dickinson, J., Haus, J. M., Lee, G. A., Hollon, C. J., Aagaard, P., ... Trappe, T. A. (2008). Influence of aging on the in vivo properties of human patellar tendon. Journal of Applied Physiology, 105(6), 1907-1915. https://doi.org/10.1152/japplphysiol.00059.2008

Influence of aging on the in vivo properties of human patellar tendon. / Carroll, C. C.; Dickinson, Jared; Haus, J. M.; Lee, G. A.; Hollon, C. J.; Aagaard, P.; Magnusson, S. P.; Trappe, T. A.

In: Journal of Applied Physiology, Vol. 105, No. 6, 12.2008, p. 1907-1915.

Research output: Contribution to journalArticle

Carroll, CC, Dickinson, J, Haus, JM, Lee, GA, Hollon, CJ, Aagaard, P, Magnusson, SP & Trappe, TA 2008, 'Influence of aging on the in vivo properties of human patellar tendon', Journal of Applied Physiology, vol. 105, no. 6, pp. 1907-1915. https://doi.org/10.1152/japplphysiol.00059.2008
Carroll CC, Dickinson J, Haus JM, Lee GA, Hollon CJ, Aagaard P et al. Influence of aging on the in vivo properties of human patellar tendon. Journal of Applied Physiology. 2008 Dec;105(6):1907-1915. https://doi.org/10.1152/japplphysiol.00059.2008
Carroll, C. C. ; Dickinson, Jared ; Haus, J. M. ; Lee, G. A. ; Hollon, C. J. ; Aagaard, P. ; Magnusson, S. P. ; Trappe, T. A. / Influence of aging on the in vivo properties of human patellar tendon. In: Journal of Applied Physiology. 2008 ; Vol. 105, No. 6. pp. 1907-1915.
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