Inactivation of viruses with a very low power visible femtosecond laser

Kong-Thon Tsen, Shaw Wei D Tsen, Chih Long Chang, Chien Fu Hung, T. C. Wu, Juliann G. Kiang

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Abstract

We demonstrate for the first time that, by using a visible femtosecond laser, it is effective to inactivate viruses such as bacteriophage M13 through impulsive stimulated Raman scattering. By using a very low power visible femtosecond laser having a wavelength of 425nm and a pulse width of 100fs, we show that M13 phages were inactivated when the laser power density was greater than or equal to 50MWcm-2. The inactivation of M13 phages was determined by plaque counts and depended on the pulse width as well as power density of the excitation laser.

Original languageEnglish (US)
Article number322102
JournalJournal of Physics Condensed Matter
Volume19
Issue number32
DOIs
StatePublished - Aug 15 2007

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ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics

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