Inactivation of viruses with a very low power visible femtosecond laser

Kong-Thon Tsen, Shaw Wei D Tsen, Chih Long Chang, Chien Fu Hung, T. C. Wu, Juliann G. Kiang

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

We demonstrate for the first time that, by using a visible femtosecond laser, it is effective to inactivate viruses such as bacteriophage M13 through impulsive stimulated Raman scattering. By using a very low power visible femtosecond laser having a wavelength of 425nm and a pulse width of 100fs, we show that M13 phages were inactivated when the laser power density was greater than or equal to 50MWcm-2. The inactivation of M13 phages was determined by plaque counts and depended on the pulse width as well as power density of the excitation laser.

Original languageEnglish (US)
Article number322102
JournalJournal of Physics Condensed Matter
Volume19
Issue number32
DOIs
StatePublished - Aug 15 2007

Fingerprint

Bacteriophages
viruses
Ultrashort pulses
Viruses
deactivation
lasers
Stimulated Raman scattering
radiant flux density
pulse duration
Laser excitation
bacteriophages
Wavelength
Lasers
Raman spectra
wavelengths
excitation

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Electronic, Optical and Magnetic Materials

Cite this

Inactivation of viruses with a very low power visible femtosecond laser. / Tsen, Kong-Thon; Tsen, Shaw Wei D; Chang, Chih Long; Hung, Chien Fu; Wu, T. C.; Kiang, Juliann G.

In: Journal of Physics Condensed Matter, Vol. 19, No. 32, 322102, 15.08.2007.

Research output: Contribution to journalArticle

Tsen, Kong-Thon ; Tsen, Shaw Wei D ; Chang, Chih Long ; Hung, Chien Fu ; Wu, T. C. ; Kiang, Juliann G. / Inactivation of viruses with a very low power visible femtosecond laser. In: Journal of Physics Condensed Matter. 2007 ; Vol. 19, No. 32.
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