In vitro effects of bryostatin 1 on the metabolism and cytotoxicity of 1-β-d-arabinofuranosylcytosine in human leukemia cells

Medicine & Life Sciences

• bryostatin 1 93%
• Cytarabine 64%
• Leukemia 46%
• Arabinofuranosylcytosine Triphosphate 45%
• In Vitro Techniques 24%
• Cell Count 22%
• Protein Kinase C 16%
• HL-60 Cells 15%
• Protein C Inhibitor 10%
• Protein Kinase Inhibitors 9%
• mezerein 7%
• Deoxycytidine Kinase 6%
• 2'-deoxycytidine 5'-triphosphate 6%
• 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 6%
• Deamination 5%
• Uridine Triphosphate 5%
• Lactones 5%
• phorbol 5%
• Staurosporine 5%
• DNA 4%
• Second Messenger Systems 4%
• Cell Extracts 4%
• Bromodeoxyuridine 4%
• Tamoxifen 4%
• Nucleosides 4%
• Thymidine 4%
• Intercellular Signaling Peptides and Proteins 3%
• Nucleotides 3%
• Adenosine Triphosphate 3%
• Cell Survival 3%
• Poisons 3%
• Temperature 3%
• Phosphorylation 3%
• Growth 2%

Chemical Compounds

• Bryostatin 1 100%
• Pharmacological Metabolism 43%
• Protein Kinase C Inhibitor 19%
• Mezerein 11%
• Antileucemic 9%
• Clonogenic 9%
• Macrocyclic Lactone 9%
• Staurosporine 9%
• dCTP 9%
• Tamoxifen 8%
• Phorbol 8%
• Proliferative 8%
• Dephosphorylation 7%
• Nucleoside Analogue 7%
• Growth Factor 7%
• Percent Reduction 7%
• Deamination 7%
• Thymidine 6%
• Toxic Substance 6%
• Neutralization 6%
• Cell Viability 6%
• Protein 5%
• Nucleotide 5%