In ovo vaccination of specific-pathogen-free chickens with vaccines containing multiple agents

Maja Gagic, Catherine A. St. Hill, J. M. Sharma

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

We used in ovo technology to protect chickens against multiple diseases by inoculating vaccines containing mixtures of live viral agents. A single in ovo injection of a vaccine containing serotypes 1, 2, and 3 of Marek's disease virus (MDV), a vaccine strain of serotype 1 infectious bursal disease virus (IBDV), and recombinant fowl pox vaccine with HN and F genes of Newcastle disease virus (rFP-NDV) induced protection against virulent MDV, IBDV, Newcastle disease virus, and fowl poxvirus. The multiple-agent vaccine induced specific antibodies against the viral agents present in the mixture and did not adversely affect the survival of hatched chickens. Inoculation of a vaccine containing serotypes 1, 2, and 3 of MDV and IBDV did not affect hatchability of eggs, although the addition of rFP-NDV to the mixture reduced hatchability by 23%-26%. In ovo vaccination with a vaccine containing MDV and IBDV vaccine viruses did not exacerbate the inhibitory effect of individual viral agents on humoral and cellular immune competence.

Original languageEnglish (US)
Pages (from-to)293-301
Number of pages9
JournalAvian Diseases
Volume43
Issue number2
StatePublished - Apr 1999
Externally publishedYes

Fingerprint

Specific Pathogen-Free Organisms
Chickens
Infectious bursal disease virus
Vaccination
Vaccines
vaccination
vaccines
chickens
Mardivirus
Marek Disease
pathogens
Viruses
Newcastle disease virus
serotypes
Marek Disease Vaccines
Fowlpox
Viral Antibodies
Poxviridae
fowl pox
egg hatchability

Keywords

  • Fowl pox
  • Immunosuppression
  • In ovo vaccination
  • Infectious bursal disease
  • Marek's disease
  • Multiple-agent vaccine
  • Newcastle disease

ASJC Scopus subject areas

  • Immunology
  • Cancer Research
  • veterinary(all)

Cite this

Gagic, M., St. Hill, C. A., & Sharma, J. M. (1999). In ovo vaccination of specific-pathogen-free chickens with vaccines containing multiple agents. Avian Diseases, 43(2), 293-301.

In ovo vaccination of specific-pathogen-free chickens with vaccines containing multiple agents. / Gagic, Maja; St. Hill, Catherine A.; Sharma, J. M.

In: Avian Diseases, Vol. 43, No. 2, 04.1999, p. 293-301.

Research output: Contribution to journalArticle

Gagic, M, St. Hill, CA & Sharma, JM 1999, 'In ovo vaccination of specific-pathogen-free chickens with vaccines containing multiple agents', Avian Diseases, vol. 43, no. 2, pp. 293-301.
Gagic, Maja ; St. Hill, Catherine A. ; Sharma, J. M. / In ovo vaccination of specific-pathogen-free chickens with vaccines containing multiple agents. In: Avian Diseases. 1999 ; Vol. 43, No. 2. pp. 293-301.
@article{ce45f18c75c5431489c4c31dcc58750c,
title = "In ovo vaccination of specific-pathogen-free chickens with vaccines containing multiple agents",
abstract = "We used in ovo technology to protect chickens against multiple diseases by inoculating vaccines containing mixtures of live viral agents. A single in ovo injection of a vaccine containing serotypes 1, 2, and 3 of Marek's disease virus (MDV), a vaccine strain of serotype 1 infectious bursal disease virus (IBDV), and recombinant fowl pox vaccine with HN and F genes of Newcastle disease virus (rFP-NDV) induced protection against virulent MDV, IBDV, Newcastle disease virus, and fowl poxvirus. The multiple-agent vaccine induced specific antibodies against the viral agents present in the mixture and did not adversely affect the survival of hatched chickens. Inoculation of a vaccine containing serotypes 1, 2, and 3 of MDV and IBDV did not affect hatchability of eggs, although the addition of rFP-NDV to the mixture reduced hatchability by 23{\%}-26{\%}. In ovo vaccination with a vaccine containing MDV and IBDV vaccine viruses did not exacerbate the inhibitory effect of individual viral agents on humoral and cellular immune competence.",
keywords = "Fowl pox, Immunosuppression, In ovo vaccination, Infectious bursal disease, Marek's disease, Multiple-agent vaccine, Newcastle disease",
author = "Maja Gagic and {St. Hill}, {Catherine A.} and Sharma, {J. M.}",
year = "1999",
month = "4",
language = "English (US)",
volume = "43",
pages = "293--301",
journal = "Avian Diseases",
issn = "0005-2086",
publisher = "American Association of Avian Pathologists",
number = "2",

}

TY - JOUR

T1 - In ovo vaccination of specific-pathogen-free chickens with vaccines containing multiple agents

AU - Gagic, Maja

AU - St. Hill, Catherine A.

AU - Sharma, J. M.

PY - 1999/4

Y1 - 1999/4

N2 - We used in ovo technology to protect chickens against multiple diseases by inoculating vaccines containing mixtures of live viral agents. A single in ovo injection of a vaccine containing serotypes 1, 2, and 3 of Marek's disease virus (MDV), a vaccine strain of serotype 1 infectious bursal disease virus (IBDV), and recombinant fowl pox vaccine with HN and F genes of Newcastle disease virus (rFP-NDV) induced protection against virulent MDV, IBDV, Newcastle disease virus, and fowl poxvirus. The multiple-agent vaccine induced specific antibodies against the viral agents present in the mixture and did not adversely affect the survival of hatched chickens. Inoculation of a vaccine containing serotypes 1, 2, and 3 of MDV and IBDV did not affect hatchability of eggs, although the addition of rFP-NDV to the mixture reduced hatchability by 23%-26%. In ovo vaccination with a vaccine containing MDV and IBDV vaccine viruses did not exacerbate the inhibitory effect of individual viral agents on humoral and cellular immune competence.

AB - We used in ovo technology to protect chickens against multiple diseases by inoculating vaccines containing mixtures of live viral agents. A single in ovo injection of a vaccine containing serotypes 1, 2, and 3 of Marek's disease virus (MDV), a vaccine strain of serotype 1 infectious bursal disease virus (IBDV), and recombinant fowl pox vaccine with HN and F genes of Newcastle disease virus (rFP-NDV) induced protection against virulent MDV, IBDV, Newcastle disease virus, and fowl poxvirus. The multiple-agent vaccine induced specific antibodies against the viral agents present in the mixture and did not adversely affect the survival of hatched chickens. Inoculation of a vaccine containing serotypes 1, 2, and 3 of MDV and IBDV did not affect hatchability of eggs, although the addition of rFP-NDV to the mixture reduced hatchability by 23%-26%. In ovo vaccination with a vaccine containing MDV and IBDV vaccine viruses did not exacerbate the inhibitory effect of individual viral agents on humoral and cellular immune competence.

KW - Fowl pox

KW - Immunosuppression

KW - In ovo vaccination

KW - Infectious bursal disease

KW - Marek's disease

KW - Multiple-agent vaccine

KW - Newcastle disease

UR - http://www.scopus.com/inward/record.url?scp=0033120942&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033120942&partnerID=8YFLogxK

M3 - Article

C2 - 10396643

AN - SCOPUS:0033120942

VL - 43

SP - 293

EP - 301

JO - Avian Diseases

JF - Avian Diseases

SN - 0005-2086

IS - 2

ER -