Immunosignaturing: A critical review

Kathryn F. Sykes, Joseph B. Legutki, Phillip Stafford

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Health is a complex interaction between metabolism, physiology, and immunity. Although it is difficult to define quantitatively, the activity of the humoral immune system provides a reasonable proxy for changes in health. Immunosignaturing is a microarray-based technology that quantitates the dynamics of circulating antibodies. Recent advancements in the field warrant a review of the technology. Here, we provide an introduction to the technique, evaluate the current progress, contrast similar technologies, and suggest applications that immunosignaturing could facilitate.

Original languageEnglish (US)
Pages (from-to)45-51
Number of pages7
JournalTrends in Biotechnology
Volume31
Issue number1
DOIs
StatePublished - Jan 2013

Fingerprint

Technology
Health
Immune system
Physiology
Proxy
Microarrays
Metabolism
Antibodies
Immune System
Immunity

Keywords

  • Antibody profiling
  • Biomarker discovery
  • Health monitoring
  • Immunodiagnostics
  • Peptide microarray

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering

Cite this

Sykes, K. F., Legutki, J. B., & Stafford, P. (2013). Immunosignaturing: A critical review. Trends in Biotechnology, 31(1), 45-51. https://doi.org/10.1016/j.tibtech.2012.10.012

Immunosignaturing : A critical review. / Sykes, Kathryn F.; Legutki, Joseph B.; Stafford, Phillip.

In: Trends in Biotechnology, Vol. 31, No. 1, 01.2013, p. 45-51.

Research output: Contribution to journalArticle

Sykes, KF, Legutki, JB & Stafford, P 2013, 'Immunosignaturing: A critical review', Trends in Biotechnology, vol. 31, no. 1, pp. 45-51. https://doi.org/10.1016/j.tibtech.2012.10.012
Sykes, Kathryn F. ; Legutki, Joseph B. ; Stafford, Phillip. / Immunosignaturing : A critical review. In: Trends in Biotechnology. 2013 ; Vol. 31, No. 1. pp. 45-51.
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