@inproceedings{d6530450e457479fa7169babebf78d7f,
title = "Immunomodulatory biomaterials to improve allogeneic islet graft survival in a murine diabetic model",
abstract = "Statement of Purpose: Type 1 diabetes (T1D) is a chronic condition in which patients produce little to no insulin due to the autoimmune progressive loss of beta cells. Whereas the disease can be managed via external insulin delivery, patients still experience a high incidence of mortality and chronic debilitating comorbidities. Islet transplantation has emerged as a potential strategy to restore a patient{\textquoteright}s glycemic control, yet long-term rejection and the need for chronic immunosuppression present a major barrier. Herein, we engineered a synthetic material to provide biological cues locally and in a controlled manner to enhance vascularization and promote long-term islet graft survival.",
author = "Coronel, {M. M.} and J. Weaver and M. Hunckler and E. Yolcu and H. Shirwan and Garc{\'i}a, {A. J.}",
year = "2019",
month = jan,
day = "1",
language = "English (US)",
series = "Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium",
publisher = "Society for Biomaterials",
booktitle = "Society for Biomaterials Annual Meeting and Exposition 2019",
note = "42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence ; Conference date: 03-04-2019 Through 06-04-2019",
}
