Identification and in silico characterisation of defective molecules associated with isolates of banana bunchy top virus

Daisy Stainton, Darren P. Martin, David A. Collings, John E. Thomas, Arvind Varsani

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Banana bunchy top virus (BBTV) is a multi-component single-stranded DNA virus. From 267 potentially infected Musa plants, 24 apparently ‘defective’ BBTV components have been identified. Interestingly, 23/24 of these defective molecules were apparently derived from DNA-R. All of the identified defective molecules had retained at least part of the CR-SL and CR-M but had insertions and/or deletions that in most cases resulted in open reading frame disruptions. Our detection of three monophyletic but diverse (and therefore likely circulating) defective DNA-R lineages suggests that, in many cases, defective DNA-R molecules might remain associated with BBTV genomes for prolonged periods.

Original languageEnglish (US)
Pages (from-to)1019-1026
Number of pages8
JournalArchives of Virology
Volume161
Issue number4
DOIs
StatePublished - Apr 1 2016
Externally publishedYes

Keywords

  • Banana bunchy top virus
  • Defective molecules
  • Nanovirus

ASJC Scopus subject areas

  • Medicine(all)
  • Virology

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