TY - JOUR
T1 - Identification and DNA sequence of the large subunit of the capping enzyme from Shope fibroma virus
AU - Upton, C.
AU - Stuart, D.
AU - McFadden, G.
N1 - Funding Information:
We thank Stewart Shuman for helpful discussions, Ed Niles for communicating results prior to publication, and Robert Maranchuk for excellent technical assistance. G.M. is supported by the Alberta Heritage Fund for Medical Research. This work was funded by operating grants from the National Cancer Institute and Medical Research Council of Canada.
PY - 1991/8
Y1 - 1991/8
N2 - A 3.6-kb region of the Shope fibroma virus (SFV) BamHI D fragment located in the central region of the viral genome was sequenced. Three open reading frames (ORFs) were identified, D3R, D4L, and D5R. Each of these ORFs have a counterpart organized identically within the HindIII fragment D of the vaccinia virus genome (D1R, D2L, and D3R). Homology scores and assays of viral cores indicate that SFV D3R encodes the large subunit of the SFV mRNA capping enzyme.
AB - A 3.6-kb region of the Shope fibroma virus (SFV) BamHI D fragment located in the central region of the viral genome was sequenced. Three open reading frames (ORFs) were identified, D3R, D4L, and D5R. Each of these ORFs have a counterpart organized identically within the HindIII fragment D of the vaccinia virus genome (D1R, D2L, and D3R). Homology scores and assays of viral cores indicate that SFV D3R encodes the large subunit of the SFV mRNA capping enzyme.
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U2 - 10.1016/0042-6822(91)91009-6
DO - 10.1016/0042-6822(91)91009-6
M3 - Article
C2 - 1649507
AN - SCOPUS:0025769407
SN - 0042-6822
VL - 183
SP - 773
EP - 777
JO - Virology
JF - Virology
IS - 2
ER -