Identification and DNA sequence of the large subunit of the capping enzyme from Shope fibroma virus

C. Upton, D. Stuart, G. McFadden

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

A 3.6-kb region of the Shope fibroma virus (SFV) BamHI D fragment located in the central region of the viral genome was sequenced. Three open reading frames (ORFs) were identified, D3R, D4L, and D5R. Each of these ORFs have a counterpart organized identically within the HindIII fragment D of the vaccinia virus genome (D1R, D2L, and D3R). Homology scores and assays of viral cores indicate that SFV D3R encodes the large subunit of the SFV mRNA capping enzyme.

Original languageEnglish (US)
Pages (from-to)773-777
Number of pages5
JournalVirology
Volume183
Issue number2
DOIs
StatePublished - Aug 1991
Externally publishedYes

ASJC Scopus subject areas

  • Virology

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