Identification and DNA sequence of the large subunit of the capping enzyme from Shope fibroma virus

C. Upton, D. Stuart, Douglas McFadden

Research output: Contribution to journalArticle

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A 3.6-kb region of the Shope fibroma virus (SFV) BamHI D fragment located in the central region of the viral genome was sequenced. Three open reading frames (ORFs) were identified, D3R, D4L, and D5R. Each of these ORFs have a counterpart organized identically within the HindIII fragment D of the vaccinia virus genome (D1R, D2L, and D3R). Homology scores and assays of viral cores indicate that SFV D3R encodes the large subunit of the SFV mRNA capping enzyme.

Original languageEnglish (US)
Pages (from-to)773-777
Number of pages5
Issue number2
StatePublished - Jan 1 1991
Externally publishedYes


ASJC Scopus subject areas

  • Virology

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