Hyperbolic geometry of the olfactory space

Yuansheng Zhou, Brian Smith, Tatyana O. Sharpee

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

In the natural environment, the sense of smell, or olfaction, serves to detect toxins and judge nutritional content by taking advantage of the associations between compounds as they are created in biochemical reactions. This suggests that the nervous system can classify odors based on statistics of their co-occurrence within natural mixtures rather than from the chemical structures of the ligands themselves. We show that this statistical perspective makes it possible to map odors to points in a hyperbolic space. Hyperbolic coordinates have a long but often underappreciated history of relevance to biology. For example, these coordinates approximate the distance between species computed along dendrograms and, more generally, between points within hierarchical tree–like networks. We find that both natural odors and human perceptual descriptions of smells can be described using a three-dimensional hyperbolic space. This match in geometries can avoid distortions that would otherwise arise when mapping odors to perception.

Original languageEnglish (US)
Article numbereaaq1458
JournalScience advances
Volume4
Issue number8
DOIs
StatePublished - Aug 29 2018

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odor
geometry
olfaction
nervous system
toxin
ligand
history

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Hyperbolic geometry of the olfactory space. / Zhou, Yuansheng; Smith, Brian; Sharpee, Tatyana O.

In: Science advances, Vol. 4, No. 8, eaaq1458, 29.08.2018.

Research output: Contribution to journalArticle

Zhou, Yuansheng ; Smith, Brian ; Sharpee, Tatyana O. / Hyperbolic geometry of the olfactory space. In: Science advances. 2018 ; Vol. 4, No. 8.
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