TY - JOUR
T1 - 'Hybrid' processing strategies for expanding and improving the synthesis of renewable bioproducts
AU - Thompson, Brian
AU - Moon, Tae Seok
AU - Nielsen, David
N1 - Funding Information:
D.R.N. is supported by the National Science Foundation (CBET-1159200, CBET- 1067684), the U.S. Department of Energy , and ASU LightWorks. T.S.M. is supported by the National Science Foundation (MCB-1331194) and the International Center for Advanced Renewable Energy & Sustainability (I-CARES).
PY - 2014/12
Y1 - 2014/12
N2 - The versatile functionality of microbial biocatalysts offers a promising solution to the growing need to replace conventional, petroleum-derived fuels, chemicals, and materials with sustainable alternatives from renewable biomass. Whereas metabolic pathway engineering and strain optimization have greatly expanded the range of attainable bioproducts, it is by coupling microbial biosynthesis with traditional chemical conversions that the diversity of products that can ultimately be derived from biomass is truly beginning to reach its full potential. As will be the focus of this short review, such 'hybrid' strategies are now facilitating the generation of new and useful value-added bioproducts from renewable sources, the likes of which have previously been unattainable via biological routes alone.
AB - The versatile functionality of microbial biocatalysts offers a promising solution to the growing need to replace conventional, petroleum-derived fuels, chemicals, and materials with sustainable alternatives from renewable biomass. Whereas metabolic pathway engineering and strain optimization have greatly expanded the range of attainable bioproducts, it is by coupling microbial biosynthesis with traditional chemical conversions that the diversity of products that can ultimately be derived from biomass is truly beginning to reach its full potential. As will be the focus of this short review, such 'hybrid' strategies are now facilitating the generation of new and useful value-added bioproducts from renewable sources, the likes of which have previously been unattainable via biological routes alone.
UR - http://www.scopus.com/inward/record.url?scp=84899857528&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84899857528&partnerID=8YFLogxK
U2 - 10.1016/j.copbio.2014.04.005
DO - 10.1016/j.copbio.2014.04.005
M3 - Review article
C2 - 24794630
AN - SCOPUS:84899857528
SN - 0958-1669
VL - 30
SP - 17
EP - 23
JO - Current Opinion in Biotechnology
JF - Current Opinion in Biotechnology
ER -