Abstract
Object: The goal of this study was to determine whether a nonpenetrating, high-density microwire array could provide sufficient information to serve as the interface for decoding motor cortical signals. Methods: Arrays of nonpenetrating microwires were implanted over the human motor cortex in 2 patients. The patients performed directed stereotypical reaching movements in 2 directions. The resulting data were used to determine whether the reach direction could be distinguished through a frequency power analysis. Results: Correlation analysis revealed decreasing signal correlation with distance. The gamma-band power during motor planning allowed binary classification of gross directionality in the reaching movements. The degree of power change was correlated to the underlying gyral pattern. Conclusions: The nonpenetrating microwire platform showed good potential for allowing differentiated signals to be recorded with high spatial fidelity without cortical penetration.
Original language | English (US) |
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Journal | Neurosurgical focus |
Volume | 27 |
Issue number | 1 |
DOIs | |
State | Published - 2009 |
Externally published | Yes |
Keywords
- Electrocorticoencephalography
- Human
- Motor cortex
- Neuroprosthesis
ASJC Scopus subject areas
- Surgery
- Clinical Neurology