HIV control in vivo: Dynamical analysis

A. B. Gumel, S. M. Moghadas

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

A deterministic model for the immunological and therapeutic control of human immunodeficiency virus (HIV) in vivo is studied qualitatively. In addition to analyzing the local stability of the equilibria, the global stability of the infection-free equilibrium is established. The optimal efficacy level of anti-retroviral therapy needed to eradicate HIV from the body of an HIV-infected individual is obtained.

Original languageEnglish (US)
Pages (from-to)561-568
Number of pages8
JournalCommunications in Nonlinear Science and Numerical Simulation
Volume9
Issue number5
DOIs
StatePublished - Oct 1 2004
Externally publishedYes

Keywords

  • Anti-retroviral therapy
  • Basic reproductive number
  • Equilibria
  • HIV
  • Stability

ASJC Scopus subject areas

  • Numerical Analysis
  • Modeling and Simulation
  • Applied Mathematics

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