High performance liquid chromatographic separation of bryostatins 1–12

George Pettit, Y. Kamano, D. Schaufelberger, C. L. Herald, P. M. Blumberg, S. W. May

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

A reversed-phase high performance liquid chromatographic (RP-8; acetonitrile-water gradient) separation procedure was developed for detecting bryostatins 1–12, using a photodiode array detector system. While bryostatins 6 and 9 were found to co-elute they were easily separated using a silica gel column with 9:1 n-hexane-n-propanol as eluent.

Original languageEnglish (US)
Pages (from-to)553-561
Number of pages9
JournalJournal of Liquid Chromatography
Volume12
Issue number4
DOIs
StatePublished - Jan 3 1989

ASJC Scopus subject areas

  • Molecular Medicine

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  • Cite this

    Pettit, G., Kamano, Y., Schaufelberger, D., Herald, C. L., Blumberg, P. M., & May, S. W. (1989). High performance liquid chromatographic separation of bryostatins 1–12. Journal of Liquid Chromatography, 12(4), 553-561. https://doi.org/10.1080/01483918908051757