High-field 1h-nmr spectral analysis of some cucurbitacins

Xinde Fang; Chun Tao Che; A. Douglas Kinghorn; Norman R. Farnsworth; Charles H. Phoebe; Benjamin Yellin; Sidney M. Hecht

doi:10.1021/np50039a010

High-field ¹h-nmr spectral analysis of some cucurbitacins

Xinde Fang, Chun Tao Che, A. Douglas Kinghorn, Norman R. Farnsworth, Charles H. Phoebe, Benjamin Yellin, Sidney M. Hecht

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

¹H-nmr spectra of the natural products cucurbitacins A, B, C, D, E, F, I, L, 23, 24-dihydrocucurbitacin F, and hexanorcucurbitacin F, as well as three acetylated derivatives, were measured at 360 MHz in pyridine-d₅. Chemical shifts and coupling constants were tabulated. In addition to all of the ring and side-chain protons, it was possible to assign several of the hydroxy group signals of these compounds. These compiled data should be useful for the structure determination of new compounds in this series.

Original language	English (US)
Pages (from-to)	429-434
Number of pages	6
Journal	Journal of Natural Products
Volume	48
Issue number	3
DOIs	https://doi.org/10.1021/np50039a010
State	Published - May 1985
Externally published	Yes

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

Access to Document

10.1021/np50039a010

Cite this

@article{6a7a5f820659481e9a8349620705f9d5,

title = "High-field 1h-nmr spectral analysis of some cucurbitacins",

abstract = "1H-nmr spectra of the natural products cucurbitacins A, B, C, D, E, F, I, L, 23, 24-dihydrocucurbitacin F, and hexanorcucurbitacin F, as well as three acetylated derivatives, were measured at 360 MHz in pyridine-d5. Chemical shifts and coupling constants were tabulated. In addition to all of the ring and side-chain protons, it was possible to assign several of the hydroxy group signals of these compounds. These compiled data should be useful for the structure determination of new compounds in this series.",

author = "Xinde Fang and Che, {Chun Tao} and Kinghorn, {A. Douglas} and Farnsworth, {Norman R.} and Phoebe, {Charles H.} and Benjamin Yellin and Hecht, {Sidney M.}",

year = "1985",

month = may,

doi = "10.1021/np50039a010",

language = "English (US)",

volume = "48",

pages = "429--434",

journal = "Journal of Natural Products",

issn = "0163-3864",

publisher = "American Chemical Society",

number = "3",

}

TY - JOUR

T1 - High-field 1h-nmr spectral analysis of some cucurbitacins

AU - Fang, Xinde

AU - Che, Chun Tao

AU - Kinghorn, A. Douglas

AU - Farnsworth, Norman R.

AU - Phoebe, Charles H.

AU - Yellin, Benjamin

AU - Hecht, Sidney M.

PY - 1985/5

Y1 - 1985/5

N2 - 1H-nmr spectra of the natural products cucurbitacins A, B, C, D, E, F, I, L, 23, 24-dihydrocucurbitacin F, and hexanorcucurbitacin F, as well as three acetylated derivatives, were measured at 360 MHz in pyridine-d5. Chemical shifts and coupling constants were tabulated. In addition to all of the ring and side-chain protons, it was possible to assign several of the hydroxy group signals of these compounds. These compiled data should be useful for the structure determination of new compounds in this series.

AB - 1H-nmr spectra of the natural products cucurbitacins A, B, C, D, E, F, I, L, 23, 24-dihydrocucurbitacin F, and hexanorcucurbitacin F, as well as three acetylated derivatives, were measured at 360 MHz in pyridine-d5. Chemical shifts and coupling constants were tabulated. In addition to all of the ring and side-chain protons, it was possible to assign several of the hydroxy group signals of these compounds. These compiled data should be useful for the structure determination of new compounds in this series.

UR - http://www.scopus.com/inward/record.url?scp=0022054927&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022054927&partnerID=8YFLogxK

U2 - 10.1021/np50039a010

DO - 10.1021/np50039a010

M3 - Article

C2 - 3839841

AN - SCOPUS:0022054927

SN - 0163-3864

VL - 48

SP - 429

EP - 434

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 3

ER -

High-field ¹h-nmr spectral analysis of some cucurbitacins

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this