Heat index flow monitoring in capillaries with interferometric backscatter detection

Joseph C. StClaire, Mark Hayes

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Independent control of fluid is important for small volume fluid applications including separation science techniques and analytical microchip devices. To effectively control fluid, a monitoring system is necessary to ensure proper response to the control input. Proof of principle for a new online technique for flow monitoring is demonstrated here. It offers near real-time measurements of small-volume flows in a noninvasive, simple, and robust design. The measurement is accomplished by the introduction of a plug of heat into the fluid and detection of the time of its appearance a short distance downstream. Using heat indexing and laser induced interferometric backscatter as the detector, flow monitoring is demonstrated in 184-μm diameter capillary tubing over a range of 2-25 cm/s (500 nL/s to 7 mL/s.).

Original languageEnglish (US)
Pages (from-to)4726-4730
Number of pages5
JournalAnalytical Chemistry
Volume72
Issue number19
StatePublished - Oct 1 2000

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Fluids
Monitoring
Tubing
Time measurement
Detectors
Hot Temperature
Lasers

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Heat index flow monitoring in capillaries with interferometric backscatter detection. / StClaire, Joseph C.; Hayes, Mark.

In: Analytical Chemistry, Vol. 72, No. 19, 01.10.2000, p. 4726-4730.

Research output: Contribution to journalArticle

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