Glycogen synthase: Key effect of exercise on insulin action

Christine Y. Christ-Roberts; Lawrence J. Mandarino

doi:10.1097/00003677-200407000-00003

Glycogen synthase: Key effect of exercise on insulin action

Christine Y. Christ-Roberts, Lawrence J. Mandarino

Research output: Contribution to journal › Review article › peer-review

22 Scopus citations

Abstract

Exercise improves insulin action in muscle, but the mechanisms are poorly characterized. Despite the notion that increased insulin signaling would accompany improved insulin sensitivity, this is not universally true. Increased activity or expression of other proteins seems to be more important. An increase in activity and expression of glycogen synthase and GLUT4 may be key to the effects of exercise.

Original language	English (US)
Pages (from-to)	90-94
Number of pages	5
Journal	Exercise and Sport Sciences Reviews
Volume	32
Issue number	3
DOIs	https://doi.org/10.1097/00003677-200407000-00003
State	Published - Jul 2004
Externally published	Yes

Keywords

Diabetes
Glucose uptake
Physical activity
Skeletal muscle

ASJC Scopus subject areas

Orthopedics and Sports Medicine
Physical Therapy, Sports Therapy and Rehabilitation

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10.1097/00003677-200407000-00003

Cite this

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abstract = "Exercise improves insulin action in muscle, but the mechanisms are poorly characterized. Despite the notion that increased insulin signaling would accompany improved insulin sensitivity, this is not universally true. Increased activity or expression of other proteins seems to be more important. An increase in activity and expression of glycogen synthase and GLUT4 may be key to the effects of exercise.",

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AB - Exercise improves insulin action in muscle, but the mechanisms are poorly characterized. Despite the notion that increased insulin signaling would accompany improved insulin sensitivity, this is not universally true. Increased activity or expression of other proteins seems to be more important. An increase in activity and expression of glycogen synthase and GLUT4 may be key to the effects of exercise.

KW - Diabetes

KW - Glucose uptake

KW - Physical activity

KW - Skeletal muscle

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Glycogen synthase: Key effect of exercise on insulin action

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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