Glycogen synthase: Key effect of exercise on insulin action

Christine Y. Christ-Roberts, Lawrence J. Mandarino

    Research output: Contribution to journalReview articlepeer-review

    21 Scopus citations


    Exercise improves insulin action in muscle, but the mechanisms are poorly characterized. Despite the notion that increased insulin signaling would accompany improved insulin sensitivity, this is not universally true. Increased activity or expression of other proteins seems to be more important. An increase in activity and expression of glycogen synthase and GLUT4 may be key to the effects of exercise.

    Original languageEnglish (US)
    Pages (from-to)90-94
    Number of pages5
    JournalExercise and Sport Sciences Reviews
    Issue number3
    StatePublished - Jul 1 2004


    • Diabetes
    • Glucose uptake
    • Physical activity
    • Skeletal muscle

    ASJC Scopus subject areas

    • Orthopedics and Sports Medicine
    • Physical Therapy, Sports Therapy and Rehabilitation


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