Abstract
In this paper, we investigate the global stability of the steady states of a general reaction-diffusion epidemiological model with infection force under intervention strategies in a spatially heterogeneous environment. We prove that the reproduction number R0 can be played an essential role in determining whether the disease will extinct or persist: if R0 < 1, there is a unique disease-free equilibrium which is globally asymptotically stable; and if R0 > 1, there exists a unique endemic equilibrium which is globally asymptotically stable. Furthermore, we study the relation between R0 with the diffusion and spatial heterogeneity and find that, it seems very necessary to create a low-risk habitat for the population to effectively control the spread of the epidemic disease. This may provide some potential applications in disease control.
Original language | English (US) |
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Pages (from-to) | 1071-1089 |
Number of pages | 19 |
Journal | Mathematical Biosciences and Engineering |
Volume | 14 |
Issue number | 5-6 |
DOIs | |
State | Published - Oct 1 2017 |
Keywords
- Basic reproduction number
- Disease-free equilibrium
- Endemic
- Spatial heterogeneity
ASJC Scopus subject areas
- Modeling and Simulation
- Agricultural and Biological Sciences(all)
- Computational Mathematics
- Applied Mathematics