Abstract
In this paper, the authors first show that if R 0 ≤ 1, the infection free steady state is globally attractive by using approaches different from those given by Min, et al.(2008). Then the authors prove that if R 0 > 1, the endemic steady state is also globally attractive. Finally, based on a patient's clinical HBV DNA data of anti-HBV infection with drug lamivudine, the authors establish an ABVIM. The numerical simulations of the ABVIM are good in agreement with the clinical data.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1221-1230 |
| Number of pages | 10 |
| Journal | Journal of Systems Science and Complexity |
| Volume | 23 |
| Issue number | 6 |
| DOIs | |
| State | Published - Dec 27 2010 |
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Keywords
- Basic infection reproduction number
- HBV infection
- clinical data simulation
- equilibrium point
- global stability
ASJC Scopus subject areas
- Computer Science (miscellaneous)
- Information Systems
Cite this
Zheng, Y., Min, L., Ji, Y., Su, Y., & Kuang, Y. (2010). Global stability of endemic equilibrium point of basic virus infection model with application to HBV infection. Journal of Systems Science and Complexity, 23(6), 1221-1230. https://doi.org/10.1007/s11424-010-8467-0