TY - JOUR
T1 - Genomic signatures of sex-biased demography
T2 - progress and prospects
AU - Webster, Timothy H.
AU - Wilson Sayres, Melissa
N1 - Publisher Copyright:
© 2016 Elsevier Ltd
PY - 2016/12/1
Y1 - 2016/12/1
N2 - Sex-biased demographic events have played a crucial role in shaping human history. Many of these processes affect genetic variation and can therefore leave detectable signatures in the genome because autosomal, X-linked, Y-linked, and mitochondrial DNA inheritance differ between sexes. Here, we discuss how sex-biased processes shape patterns of genetic diversity across the genome, review recent genomic evidence for sex-biased demography in modern human populations, and suggest directions for future research.
AB - Sex-biased demographic events have played a crucial role in shaping human history. Many of these processes affect genetic variation and can therefore leave detectable signatures in the genome because autosomal, X-linked, Y-linked, and mitochondrial DNA inheritance differ between sexes. Here, we discuss how sex-biased processes shape patterns of genetic diversity across the genome, review recent genomic evidence for sex-biased demography in modern human populations, and suggest directions for future research.
UR - http://www.scopus.com/inward/record.url?scp=84985018952&partnerID=8YFLogxK
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U2 - 10.1016/j.gde.2016.08.002
DO - 10.1016/j.gde.2016.08.002
M3 - Review article
C2 - 27599147
AN - SCOPUS:84985018952
SN - 0959-437X
VL - 41
SP - 62
EP - 71
JO - Current Opinion in Genetics and Development
JF - Current Opinion in Genetics and Development
ER -