Genomic comparison of the ants Camponotus floridanus and Harpegnathos saltator

Roberto Bonasio, Guojie Zhang, Chaoyang Ye, Navdeep S. Mutti, Xiaodong Fang, Nan Qin, Greg Donahue, Pengcheng Yang, Qiye Li, Cai Li, Pei Zhang, Zhiyong Huang, Shelley L. Berger, Danny Reinberg, Jun Wang, Juergen Liebig

Research output: Contribution to journalArticlepeer-review

320 Scopus citations

Abstract

The organized societies of ants include short-lived worker castes displaying specialized behavior and morphology and long-lived queens dedicated to reproduction. We sequenced and compared the genomes of two socially divergent ant species: Camponotus floridanus and Harpegnathos saltator. Both genomes contained high amounts of CpG, despite the presence of DNA methylation, which in non-Hymenoptera correlates with CpG depletion. Comparison of gene expression in different castes identified up-regulation of telomerase and sirtuin deacetylases in longer-lived H. saltator reproductives, caste-specific expression of microRNAs and SMYD histone methyltransferases, and differential regulation of genes implicated in neuronal function and chemical communication. Our findings provide clues on the molecular differences between castes in these two ants and establish a new experimental model to study epigenetics in aging and behavior.

Original languageEnglish (US)
Pages (from-to)1068-1071
Number of pages4
JournalScience
Volume329
Issue number5995
DOIs
StatePublished - Aug 27 2010

ASJC Scopus subject areas

  • General

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