Genetic vaccination against murine cysticercosis by using a plasmid vector carrying Taenia solium paramyosin

Carlos F. Solís, Pedro Ostoa-Saloma, Verónica H. Lugo-Martínez, Stephen Albert Johnston, Juan Pedro Laclette

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

A plasmid vector carrying the immunoprotective amino-terminal fragment of Taenia solium paramyosin (VW2-1) was designed for genetic vaccination studies. Mice that were genetically immunized with VW2-1 and challenged by intraperitoneal inoculation of Taenia crassiceps cysticerci showed 43 to 48% reductions in the parasite burden, values which were similar to values obtained previously when the recombinant protein was used.

Original languageEnglish (US)
Pages (from-to)1895-1897
Number of pages3
JournalInfection and immunity
Volume73
Issue number3
DOIs
StatePublished - Mar 2005
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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