TY - JOUR
T1 - Genetic vaccination against murine cysticercosis by using a plasmid vector carrying Taenia solium paramyosin
AU - Solís, Carlos F.
AU - Ostoa-Saloma, Pedro
AU - Lugo-Martínez, Verónica H.
AU - Johnston, Stephen Albert
AU - Laclette, Juan Pedro
PY - 2005/3
Y1 - 2005/3
N2 - A plasmid vector carrying the immunoprotective amino-terminal fragment of Taenia solium paramyosin (VW2-1) was designed for genetic vaccination studies. Mice that were genetically immunized with VW2-1 and challenged by intraperitoneal inoculation of Taenia crassiceps cysticerci showed 43 to 48% reductions in the parasite burden, values which were similar to values obtained previously when the recombinant protein was used.
AB - A plasmid vector carrying the immunoprotective amino-terminal fragment of Taenia solium paramyosin (VW2-1) was designed for genetic vaccination studies. Mice that were genetically immunized with VW2-1 and challenged by intraperitoneal inoculation of Taenia crassiceps cysticerci showed 43 to 48% reductions in the parasite burden, values which were similar to values obtained previously when the recombinant protein was used.
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UR - http://www.scopus.com/inward/citedby.url?scp=15544376102&partnerID=8YFLogxK
U2 - 10.1128/IAI.73.3.1895-1897.2005
DO - 10.1128/IAI.73.3.1895-1897.2005
M3 - Article
C2 - 15731096
AN - SCOPUS:15544376102
SN - 0019-9567
VL - 73
SP - 1895
EP - 1897
JO - Infection and immunity
JF - Infection and immunity
IS - 3
ER -