Genetic structure of chimpanzee populations.

Celine Becquet, Nick Patterson, Anne Stone, Molly Przeworski, David Reich

Research output: Contribution to journalArticle

114 Citations (Scopus)

Abstract

Little is known about the history and population structure of our closest living relatives, the chimpanzees, in part because of an extremely poor fossil record. To address this, we report the largest genetic study of the chimpanzees to date, examining 310 microsatellites in 84 common chimpanzees and bonobos. We infer three common chimpanzee populations, which correspond to the previously defined labels of "western," "central," and "eastern," and find little evidence of gene flow between them. There is tentative evidence for structure within western chimpanzees, but we do not detect distinct additional populations. The data also provide historical insights, demonstrating that the western chimpanzee population diverged first, and that the eastern and central populations are more closely related in time.

Original languageEnglish (US)
JournalPLoS Genetics
Volume3
Issue number4
DOIs
StatePublished - Apr 20 2007

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Pan troglodytes
Genetic Structures
fossil record
genetic structure
gene flow
population structure
history
Population
Pan paniscus
Fossils
Gene Flow
Microsatellite Repeats
fossils
History
microsatellite repeats

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Ecology, Evolution, Behavior and Systematics
  • Cancer Research
  • Genetics(clinical)

Cite this

Genetic structure of chimpanzee populations. / Becquet, Celine; Patterson, Nick; Stone, Anne; Przeworski, Molly; Reich, David.

In: PLoS Genetics, Vol. 3, No. 4, 20.04.2007.

Research output: Contribution to journalArticle

Becquet, C, Patterson, N, Stone, A, Przeworski, M & Reich, D 2007, 'Genetic structure of chimpanzee populations.', PLoS Genetics, vol. 3, no. 4. https://doi.org/10.1371/journal.pgen.0030066
Becquet, Celine ; Patterson, Nick ; Stone, Anne ; Przeworski, Molly ; Reich, David. / Genetic structure of chimpanzee populations. In: PLoS Genetics. 2007 ; Vol. 3, No. 4.
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