The spine plays an essential biomechanical role, and disruptions to the structure of the vertebral column can have profound clinical consequences. The structure of the spine is patterned early in embryonic development with the formation of transient segmental structures called somites. Developmental studies have helped to identify the genetic pathways regulating this process and the mutations that lead to severe congenital vertebral.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)