Genetic characterization of wild and captive rhesus macaques in China

J. Satkoski, D. George, D. G. Smith, Sree Kanthaswamy

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

The genetic structures of wild and captive rhesus macaque populations within China were compared by analyzing the mtDNA sequences of 203 captive-bred Chinese rhesus macaques with 77 GenBank sequences from wild-caught animals trapped throughout China. The genotypes of 22 microsatellites of captive Chinese rhesus macaques were also compared with those of captive Indian animals. The Chinese population is significantly differentiated from the Indian population and is more heterogeneous. Thus, compared with Indian rhesus macaques the phenotypic variance of traits with high heritability will be inflated in Chinese animals. Our data suggest that the western Chinese provinces have more subdivided populations than the eastern and southern Chinese provinces. The southern Chinese populations are the least structured and might have been more recently established. Human-mediated interbreeding among captive Chinese populations has occurred, implying that Chinese breeding strategies can influence the interpretation of biomedical research in the USA.

Original languageEnglish (US)
Pages (from-to)67-80
Number of pages14
JournalJournal of Medical Primatology
Volume37
Issue number2
DOIs
StatePublished - Apr 1 2008
Externally publishedYes

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Keywords

  • Admixture
  • Colony management
  • Geographic origin
  • Microsatellites
  • Mitochondrial DNA

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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