Genetic analysis of riboswitch-mediated transcriptional regulation responding to Mn2+ in Salmonella

Yixin Shi, Guang Zhao, Wei Kong

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Background: Divalent cation binding to riboswitch RNAs regulates expression of their transporter genes in bacteria. Results:Mn2+ interacts with Salmonella riboswitches characterized fromMn2+ transporter mntH andMg2+ transporter mgtA to modulate transcription of the downstream coding region. Conclusion: Specific riboswitches control gene expression in response to Mn2+ in bacteria. Significance: This is the discovery of a Mn2+ riboswitch.

Original languageEnglish (US)
Pages (from-to)11353-11366
Number of pages14
JournalJournal of Biological Chemistry
Volume289
Issue number16
DOIs
StatePublished - Apr 18 2014

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

Fingerprint Dive into the research topics of 'Genetic analysis of riboswitch-mediated transcriptional regulation responding to Mn<sup>2+</sup> in Salmonella'. Together they form a unique fingerprint.

Cite this