Gene expression profiles of fathead minnows exposed to surface waters above and below a sewage treatment plant in Minnesota

Natàlia Garcia-Reyero, Ira Adelman, Li Liu, Nancy Denslow

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Water treatment plants are often not effective in removing pharmaceuticals, personal care products or natural hormones from their effluents. To test the effects of these effluents on fish, we exposed male fathead minnows (Pimephales promelas) for 48 h to effluents at two sites, one up-stream and the other down-stream from a water treatment plant. Gene expression profiling showed that significant changes occurred in the gonad of fish exposed below, compared to above the treatment plant and to laboratory control fish. Among the biological processes affected were the innate immune response, response to stress, control of homeostasis, control of transcription, metabolism, and cell communication. This work suggests that fish are impacted by exposures to the sewage treatment effluents and effects can be detected rapidly by gene expression profiling.

Original languageEnglish (US)
Pages (from-to)134-136
Number of pages3
JournalMarine Environmental Research
Volume66
Issue number1
DOIs
StatePublished - Jul 2008
Externally publishedYes

Fingerprint

Sewage treatment plants
Pimephales promelas
sewage treatment
Surface waters
Gene expression
Fish
gene expression
effluents
Effluents
surface water
effluent
Water treatment plants
fish
water treatment
personal care products
cell communication
Sewage treatment
Hormones
homeostasis
Transcription

Keywords

  • Gene expression profiling
  • Pharmaceuticals
  • Sewage treatment plants

ASJC Scopus subject areas

  • Aquatic Science
  • Oceanography
  • Environmental Science(all)

Cite this

Gene expression profiles of fathead minnows exposed to surface waters above and below a sewage treatment plant in Minnesota. / Garcia-Reyero, Natàlia; Adelman, Ira; Liu, Li; Denslow, Nancy.

In: Marine Environmental Research, Vol. 66, No. 1, 07.2008, p. 134-136.

Research output: Contribution to journalArticle

@article{3c11efd13414460f8f2e8e01e86d183e,
title = "Gene expression profiles of fathead minnows exposed to surface waters above and below a sewage treatment plant in Minnesota",
abstract = "Water treatment plants are often not effective in removing pharmaceuticals, personal care products or natural hormones from their effluents. To test the effects of these effluents on fish, we exposed male fathead minnows (Pimephales promelas) for 48 h to effluents at two sites, one up-stream and the other down-stream from a water treatment plant. Gene expression profiling showed that significant changes occurred in the gonad of fish exposed below, compared to above the treatment plant and to laboratory control fish. Among the biological processes affected were the innate immune response, response to stress, control of homeostasis, control of transcription, metabolism, and cell communication. This work suggests that fish are impacted by exposures to the sewage treatment effluents and effects can be detected rapidly by gene expression profiling.",
keywords = "Gene expression profiling, Pharmaceuticals, Sewage treatment plants",
author = "Nat{\`a}lia Garcia-Reyero and Ira Adelman and Li Liu and Nancy Denslow",
year = "2008",
month = "7",
doi = "10.1016/j.marenvres.2008.02.073",
language = "English (US)",
volume = "66",
pages = "134--136",
journal = "Marine Environmental Research",
issn = "0141-1136",
publisher = "Elsevier BV",
number = "1",

}

TY - JOUR

T1 - Gene expression profiles of fathead minnows exposed to surface waters above and below a sewage treatment plant in Minnesota

AU - Garcia-Reyero, Natàlia

AU - Adelman, Ira

AU - Liu, Li

AU - Denslow, Nancy

PY - 2008/7

Y1 - 2008/7

N2 - Water treatment plants are often not effective in removing pharmaceuticals, personal care products or natural hormones from their effluents. To test the effects of these effluents on fish, we exposed male fathead minnows (Pimephales promelas) for 48 h to effluents at two sites, one up-stream and the other down-stream from a water treatment plant. Gene expression profiling showed that significant changes occurred in the gonad of fish exposed below, compared to above the treatment plant and to laboratory control fish. Among the biological processes affected were the innate immune response, response to stress, control of homeostasis, control of transcription, metabolism, and cell communication. This work suggests that fish are impacted by exposures to the sewage treatment effluents and effects can be detected rapidly by gene expression profiling.

AB - Water treatment plants are often not effective in removing pharmaceuticals, personal care products or natural hormones from their effluents. To test the effects of these effluents on fish, we exposed male fathead minnows (Pimephales promelas) for 48 h to effluents at two sites, one up-stream and the other down-stream from a water treatment plant. Gene expression profiling showed that significant changes occurred in the gonad of fish exposed below, compared to above the treatment plant and to laboratory control fish. Among the biological processes affected were the innate immune response, response to stress, control of homeostasis, control of transcription, metabolism, and cell communication. This work suggests that fish are impacted by exposures to the sewage treatment effluents and effects can be detected rapidly by gene expression profiling.

KW - Gene expression profiling

KW - Pharmaceuticals

KW - Sewage treatment plants

UR - http://www.scopus.com/inward/record.url?scp=44749087321&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=44749087321&partnerID=8YFLogxK

U2 - 10.1016/j.marenvres.2008.02.073

DO - 10.1016/j.marenvres.2008.02.073

M3 - Article

C2 - 18417205

AN - SCOPUS:44749087321

VL - 66

SP - 134

EP - 136

JO - Marine Environmental Research

JF - Marine Environmental Research

SN - 0141-1136

IS - 1

ER -