Gametic disequilibrium and multilocus estimation of selfing rates

Philip W. Hedrick, Kermit Ritlandt

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

The influence of disequilibrium between loci on multilocus estimates of the selfing (or outcrossing) rate has been examined. In general, there is a negative bias in estimating the outcrossing rate when there is disequilibrium but under certain conditions, there may be a small positive bias. When attempting to estimate the extent of biparentai inbreeding using a comparison of the multilocus and single-locus estimates of outcrossing, the general negative bias caused by disequilibrium will result in an underdetection of biparentai inbreeding.

Original languageEnglish (US)
Pages (from-to)343-347
Number of pages5
JournalHeredity
Volume65
Issue number3
DOIs
StatePublished - 1990
Externally publishedYes

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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