From molecular to modular cell biology

Leland Hartwell, J. J. Hopfield, S. Leibler, A. W. Murray

Research output: Contribution to journalArticle

2436 Citations (Scopus)

Abstract

Cellular functions, such as signal transmission, are carried out by 'modules' made up of many species of interacting molecules. Understanding how modules work has depended on combining phenomenological analysis with molecular studies. General principles that govern the structure and behaviour of modules may be discovered with help from synthetic sciences such as engineering and computer science, from stronger interactions between experiment and theory in cell biology, and from an appreciation of evolutionary constraints.

Original languageEnglish (US)
JournalNature
Volume402
Issue number6761 SUPPL.
StatePublished - Dec 2 1999
Externally publishedYes

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Cell Biology

ASJC Scopus subject areas

  • General

Cite this

Hartwell, L., Hopfield, J. J., Leibler, S., & Murray, A. W. (1999). From molecular to modular cell biology. Nature, 402(6761 SUPPL.).

From molecular to modular cell biology. / Hartwell, Leland; Hopfield, J. J.; Leibler, S.; Murray, A. W.

In: Nature, Vol. 402, No. 6761 SUPPL., 02.12.1999.

Research output: Contribution to journalArticle

Hartwell, L, Hopfield, JJ, Leibler, S & Murray, AW 1999, 'From molecular to modular cell biology', Nature, vol. 402, no. 6761 SUPPL..
Hartwell L, Hopfield JJ, Leibler S, Murray AW. From molecular to modular cell biology. Nature. 1999 Dec 2;402(6761 SUPPL.).
Hartwell, Leland ; Hopfield, J. J. ; Leibler, S. ; Murray, A. W. / From molecular to modular cell biology. In: Nature. 1999 ; Vol. 402, No. 6761 SUPPL.
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