@inproceedings{99a0d5cabdd541f19d23a527d0627f23,
title = "Forming self-assembled cell arrays and measuring the oxygen consumption rate of a single live cell",
abstract = "We report a method for forming arrays of live single cells on a chip using polymer micro-traps made of SU8. We have studied the toxicity of the microfabricated structures and the associated environment for two cell lines. We also report a method for measuring the oxygen consumption rate of a single cell using optical interrogation of molecular oxygen sensors placed in micromachined micro-wells by temporarily sealing the cells in the micro-traps. The new techniques presented here add to the collection of tools available for performing {"}single-cell{"} biology. A single-cell self-assembly yield of 61% was achieved with oxygen draw down rates of 0.83, 0.82, and 0.71 fmol/minute on three isolated live A549 cells.",
keywords = "Microfluidics, Oxygen measurement, SU8 toxicity, Self-assembly, Single-cell",
author = "Etzkorn, {James R.} and McQuaide, {Sarah C.} and Anderson, {Judy B.} and Deirdre Meldrum and Parviz, {Babak A.}",
note = "Copyright: Copyright 2009 Elsevier B.V., All rights reserved.; TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems ; Conference date: 21-06-2009 Through 25-06-2009",
year = "2009",
doi = "10.1109/SENSOR.2009.5285450",
language = "English (US)",
isbn = "9781424441938",
series = "TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems",
pages = "2374--2377",
booktitle = "TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems",
}