Formation and dissolution of hen egg white lysozyme amyloid fibrils in protic ionic liquids

Nolene Byrne, Charles Angell

Research output: Contribution to journalArticle

76 Scopus citations

Abstract

The formation of amyloid fibrils from non-disease-related proteins demonstrates that any protein can adopt this "rogue" form; we show that it is possible to use protic ionic liquids to fibrilize hen egg white lysozyme, and then subsequently to dissolve the fibrils with up to 72% restoration of enzymatic activity.

Original languageEnglish (US)
Pages (from-to)1046-1048
Number of pages3
JournalChemical Communications
Issue number9
DOIs
StatePublished - 2009

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Fingerprint Dive into the research topics of 'Formation and dissolution of hen egg white lysozyme amyloid fibrils in protic ionic liquids'. Together they form a unique fingerprint.

  • Cite this