Fish polyomaviruses belong to two distinct evolutionary lineages

Koenraad Van Doorslaer, Simona Kraberger, Charlotte Austin, Kata Farkas, Melissa Bergeman, Emma Paunil, William Davison, Arvind Varsani

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

The Polyomaviridae is a diverse family of circular double-stranded DNA viruses. Polyomaviruses have been isolated from a wide array of animal hosts. An understanding of the evolutionary and ecological dynamics of these viruses is essential to understanding the pathogenicity of polyomaviruses. Using a high throughput sequencing approach, we identified a novel polyomavirus in an emerald notothen (Trematomus bernacchii) sampled in the Ross sea (Antarctica), expanding the known number of fish-associated polyomaviruses. Our analysis suggests that polyomaviruses belong to three main evolutionary clades; the first clade is made up of all recognized terrestrial polyomaviruses. The fish-associated polyomaviruses are not monophyletic, and belong to two divergent evolutionary lineages. The fish viruses provide evidence that the evolution of the key viral large T protein involves gain and loss of distinct domains.

Original languageEnglish (US)
Pages (from-to)567-573
Number of pages7
JournalJournal of General Virology
Volume99
Issue number4
DOIs
StatePublished - Apr 1 2018

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Keywords

  • Antarctica
  • Emerald notothen
  • Polyomaviridae
  • Trematomus bernacchii

ASJC Scopus subject areas

  • Virology

Cite this

Van Doorslaer, K., Kraberger, S., Austin, C., Farkas, K., Bergeman, M., Paunil, E., Davison, W., & Varsani, A. (2018). Fish polyomaviruses belong to two distinct evolutionary lineages. Journal of General Virology, 99(4), 567-573. https://doi.org/10.1099/jgv.0.001041