Field ionization mass spectrometry—I. Nucleosides

Peter Brown, George Pettit, Roland K. Robins

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

The field ionization mass spectra of a series of nucleosides are reported, and compared with spectra obtained by conventional electron‐impact ionization. The latter are complex, with structurally significant molecular ion and sugar cleavage peaks often of low intensity or completely absent. In contrast, the field ion spectra are extremely simple, with all except guanosine (highest mass peak [M — 18]) showing intense molecular ion peaks, and the characteristic sugar (S) and base (B + H) cleavage products as the only other important fragments.

Original languageEnglish (US)
Pages (from-to)521-531
Number of pages11
JournalOrganic Mass Spectrometry
Volume2
Issue number5
DOIs
StatePublished - 1969

Fingerprint

nucleosides
Nucleosides
Ionization
Ions
sugars
molecular ions
Sugars
ionization
cleavage
guanosines
Guanosine
mass spectra
fragments
products
ions

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Instrumentation

Cite this

Field ionization mass spectrometry—I. Nucleosides. / Brown, Peter; Pettit, George; Robins, Roland K.

In: Organic Mass Spectrometry, Vol. 2, No. 5, 1969, p. 521-531.

Research output: Contribution to journalArticle

Brown, Peter ; Pettit, George ; Robins, Roland K. / Field ionization mass spectrometry—I. Nucleosides. In: Organic Mass Spectrometry. 1969 ; Vol. 2, No. 5. pp. 521-531.
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